The island has been inhabited since ancient times, as has been proved by the finds made in the Episkopi ad". 

The only road on Sikinos links Alopronia, the island's harbour, with Hora or Kastro, one of the most beautiful villages anywhere in the Cyclades. There are fine stone mansions to admire, and a church of Our Lady 'Pantanassa'. The Zoodoho. Pigi monastery, built on the peak of a rock, is more reminiscent of an impregnable castle from a distance. As on all the more isolated Cycladic islands, the local religious feasts are celebrated with great enthusiasm. There are a few rooms for rent on Sikinos, all of them in Hora. Basic meals are served at the island's restaurants and tavernas